Covid19treatmentguidelines.nih.gov

COVID-19 Treatment Guidelines

The guidelines for the diagnosis, treatment, and control of the coronavirus disease 2019 (COVID-19).

Actived: 7 days ago

URL: https://www.covid19treatmentguidelines.nih.gov/

Overview COVID-19 Treatment Guidelines

(6 days ago) Among those with available data on health conditions, 32% had cardiovascular disease, 30% had diabetes, and 18% had chronic lung disease. Other conditions that may lead to a high risk for severe COVID-19 include cancer, kidney disease, obesity, sickle cell disease, and other immunocompromising conditions.

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What's new COVID-19 Treatment Guidelines

(7 days ago) The Coronavirus Disease 2019 (COVID-19) Treatment Guidelines is published in an electronic format that can be updated in step with the rapid pace and growing volume of information regarding the treatment of COVID-19.

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Coronavirus Disease 2019 (COVID-19) Treatment Guidelines

(Just Now) that health care providers, patients, and policy experts have the most recent information regarding the optimal management of COVID-19 (see the Panel Roster for a list of Panel members). New Guidelines sections and recommendations and updates to existing Guidelines sections are developed by working groups of Panel members.

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Outpatient Management COVID-19 Treatment Guidelines

(9 days ago) The COVID-19 Treatment Guidelines Panel (the Panel) recognizes that the distinction between outpatient and inpatient care may be less clear during the COVID-19 pandemic. Patients with COVID-19 may receive care outside traditional ambulatory care or hospital settings amid the rising number of COVID-19 hospitalizations across the country.

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Clinical Spectrum COVID-19 Treatment Guidelines

(4 days ago) Among the 274 respondents who were symptomatic at the time of testing, 35% reported not having returned to their usual state of health 2 weeks or more after testing; 26% among patients aged 18 to 34 years, 32% among those aged 35 to 49 years, and 47% among those aged ≥50 years. 23 An age of ≥50 years and the presence of three or more

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Prevention of SARS-CoV-2 COVID-19 Treatment Guidelines

(1 days ago) Summary Recommendations The COVID-19 Treatment Guidelines Panel (the Panel) recommends against the use of any drugs for SARS-CoV-2 pre-exposure prophylaxis (PrEP), except in a clinical trial (AIII). The Panel recommends against the use of hydroxychloroquine for SARS-CoV-2 post-exposure prophylaxis (PEP) (AI).

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Anti-SARS-CoV-2 Monoclonal Antibodies COVID-19 Treatment

(9 days ago) The COVID-19 Treatment Guidelines Panel (the Panel) recommends using one of the following anti-SARS-CoV-2 monoclonal antibody combinations (listed in alphabetical order) to treat outpatients with mild to moderate COVID-19 who are at high risk …

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Ivermectin COVID-19 Treatment Guidelines

(6 days ago) Ivermectin. Last Updated: February 11, 2021. Ivermectin is a Food and Drug Administration (FDA)-approved antiparasitic drug that is used to treat several neglected tropical diseases, including onchocerciasis, helminthiases, and scabies. 1 It is also being evaluated for its potential to reduce the rate of malaria transmission by killing mosquitoes that feed on treated humans and …

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Interleukin-6 Inhibitors COVID-19 Treatment Guidelines

(9 days ago) Given the paucity of data, current recommendations advise against the use of tocilizumab during pregnancy. 16 Decisions about tocilizumab administration during pregnancy must include shared decision-making between the pregnant individual and their health care provider, considering potential maternal benefit and fetal risks. Considerations in

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Concomitant Medications COVID-19 Treatment Guidelines

(1 days ago) The COVID-19 Treatment Guidelines Panel (the Panel) recommends against the use of ACE inhibitors or ARBs for the treatment of COVID-19, except in a clinical trial (AIII). These recommendations are in accord with a joint statement of the American Heart Association, the Heart Failure Society of America, and the American College of Cardiology. 1

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Therapeutic Management COVID-19 Treatment Guidelines

(Just Now) The COVID-19 Treatment Guidelines Panel (the Panel) recommends providing supportive care and symptomatic management to outpatients with COVID-19; steps should also be taken to reduce the risk of SARS-CoV-2 transmission to others. 1,2 Patients should be advised about when to seek in-person evaluation.

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Panel Roster Coronavirus Disease COVID-19

(Just Now) University of Texas Southwestern/Veterans Affairs North Texas Health Care System, Dallas, TX Pamela S. Belperio, PharmD Department of Veterans Affairs, Los Angeles, CA

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Oxygenation and Ventilation COVID-19 Treatment Guidelines

(9 days ago) For adults with COVID-19 and acute hypoxemic respiratory failure despite conventional oxygen therapy, the Panel recommends high-flow nasal cannula (HFNC) oxygen over noninvasive positive pressure ventilation (NIPPV) (BIIa).

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Remdesivir COVID-19 Treatment Guidelines

(6 days ago) Remdesivir should be administered in a hospital or a health care setting that can provide a similar level of care to an inpatient hospital. Remdesivir has been studied in several clinical trials for the treatment of COVID-19. The recommendations from the COVID-19 Treatment Guidelines Panel (the Panel) are based on the results of these studies.

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Guidelines Introduction COVID-19 Treatment Guidelines

(Just Now) Panel members include representatives from federal agencies, health care and academic organizations, and professional societies. Federal agencies and professional societies represented on the Panel include: American Association of Critical-Care Nurses ; American Association for Respiratory Care ; American College of Chest Physicians

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SARS-CoV-2 Testing COVID-19 Treatment Guidelines

(5 days ago) Serologic assays that have FDA EUAs should be used for public health and clinical use. Formal comparisons of serologic tests are in progress. Two types of serologic tests have received EUAs from the FDA. The first type are antibody tests that detect the presence of binding antibodies, which bind to a pathogen (e.g., a virus). The second type of

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Colchicine COVID-19 Treatment Guidelines

(5 days ago) Colchicine. Last Updated: April 21, 2021. Colchicine is an anti-inflammatory drug that is used to treat a variety of conditions, including gout, recurrent pericarditis, and familial Mediterranean fever. 1 Recently, the drug has been studied for the prevention of major cardiovascular events in those with coronary artery disease. 2 Colchicine has several potential mechanisms of action, including

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Antiviral Therapy COVID-19 Treatment Guidelines

(5 days ago) As in the management of any disease, treatment decisions ultimately reside with the patient and their health care provider. For more information on these antiviral agents, see Table 2d. Remdesivir. See Therapeutic Management of Patients with COVID-19 for recommendations on using remdesivir with or without dexamethasone.

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Vitamin D COVID-19 Treatment Guidelines

(9 days ago) Read information about vitamin D and COVID-19. Vitamin D. Last Updated: April 21, 2021. Recommendation. There are insufficient data to recommend either for or against the use of vitamin D for the prevention or treatment of COVID-19.

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Influenza and COVID-19 Coronavirus Disease COVID-19

(7 days ago) Summary Recommendations; Summary Recommendations Influenza Vaccination. Although data are lacking on influenza vaccination for persons with COVID-19, on the basis of practice for other acute respiratory infections, the Panel recommends that persons with COVID-19 should receive an inactivated influenza vaccine (BIII).The Centers for Disease Control and Prevention (CDC) has …

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Antithrombotic Therapy COVID-19 Treatment Guidelines

(Just Now) Association Between COVID-19 and Thromboembolism. Infection with the novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and the resulting syndrome, COVID-19, have been associated with inflammation and a prothrombotic state, with increases in fibrin, fibrin degradation products, fibrinogen, and D-dimers. 1,2 In some studies, elevations in these markers have been …

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Fluvoxamine COVID-19 Treatment Guidelines

(6 days ago) Fluvoxamine. Last Updated: April 23, 2021. Fluvoxamine is a selective serotonin reuptake inhibitor (SSRI) that is approved by the Food and Drug Administration (FDA) for the treatment of obsessive-compulsive disorder and is used for other conditions, including depression.

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Zinc COVID-19 Treatment Guidelines

(4 days ago) Zinc. Last Updated: April 21, 2021. Recommendations. There are insufficient data for the COVID-19 Treatment Guidelines Panel (the Panel) to recommend either for or against the use of zinc for the treatment of COVID-19.

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The National Institutes of Health COVID-19 Treatment

(2 days ago) The National Institutes of Health COVID-19 Treatment Guidelines Panel Provides Recommendations for Dexamethasone in Patients with COVID-19 (Last updated June 25, 2020) Introduction Patients with severe COVID-19 develop a systemic inflammatory response that can lead to lung injury and multisystem organ dysfunction.

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Outpatient Management of Acute COVID-19

(3 days ago) Health care providers should identify patients who are at risk for disease progression and ensure that these patients receive adequate medical follow-up. The frequency and duration of follow-up will depend on the risk for severe disease, the severity of symptoms, and …

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HIV COVID-19 Treatment Guidelines

(1 days ago) In addition to these Guidelines, the Department of Health and Human Services (HHS) Panel on Antiretroviral Guidelines for Adults and Adolescents has developed the Interim Guidance for COVID-19 and Persons with HIV. Clinical Outcomes of COVID-19 in People With HIV. Data are emerging on the clinical outcomes of COVID-19 in people with HIV.

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Children COVID-19 Treatment Guidelines

(6 days ago) Epidemiology. Data from the Centers for Disease Control and Prevention (CDC) demonstrate a lower incidence of SARS-CoV-2 infection and severe disease in children than in adults. 1 However, without more systematic testing for children, including for children with mild symptoms as part of contact tracing, or seroprevalence studies, the true burden of pediatric SARS-CoV-2 infection …

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Convalescent Plasma and Immune Globulins COVID-19

(1 days ago) The COVID-19 Treatment Guidelines Panel (the Panel) recommends against the use of low-titer COVID-19 convalescent plasma for the treatment of COVID-19 (AIIb). Low-titer COVID-19 convalescent plasma is no longer authorized through the convalescent plasma EUA. For Hospitalized Patients With COVID-19 Who Do Not Have Impaired Immunity

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Last Updated: December 17, 2020

(2 days ago) • For health care workers who are performing aerosol-generating procedures on patients with COVID-19, the COVID-19 Treatment Guidelines Panel (the Panel) recommends using an N95 respirator (or equivalent or higher-level respirator) rather than surgical masks, in addition to other personal protective equipment (PPE) (i.e., gloves, gown, and eye

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Infection Control in Healthcare COVID-19 Treatment

(9 days ago) For health care workers who are providing usual care for nonventilated patients with COVID-19, the Panel recommends using an N95 respirator (or equivalent or higher-level respirator) or a surgical mask, in addition to other PPE (i.e., gloves, gown, and eye protection such as a face shield or safety goggles) (AIIa).

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The COVID-19 Treatment Guidelines Panel’s Statement on the

(3 days ago) Health care providers are encouraged to discuss participation in bamlanivimab clinical trials with their patients. • Given the possibility of a limited supply of bamlanivimab, as well as challenges distributing and administering the drug, patients at highest …

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Appendix A, Table 1. COVID-19 Treatment Guidelines Panel

(2 days ago) Carl Hinkson, MSRC Providence Health & Services, Everett, WA Brenna L. Hughes, MD, MSc Duke University School of Medicine, Durham, NC Steven Johnson, MD University of Colorado School of Medicine, Aurora, CO Marla J. Keller, MD Albert Einstein College of …

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Corticosteroids COVID-19 Treatment Guidelines

(Just Now) Corticosteroids. Last Updated: November 3, 2020. Patients with severe COVID-19 can develop a systemic inflammatory response that can lead to …

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COVID-19 and Special Populations

(2 days ago) COVID-19 Treatment Guidelines 277 Special Considerations in Pregnancy Last Updated: August 27, 2020 Epidemiology of COVID-19 in Pregnancy Initial reports of COVID-19 disease acquired in the third trimester were reassuring, although most early

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Antiviral Drugs That Are Approved or Under Evaluation for

(2 days ago) should be administered in a hospital or a health care setting that can provide a similar level of care to an inpatient hospital. Remdesivir has been studied in several clinical trials for the treatment of COVID-19. The recommendations from the COVID-19 Treatment Guidelines Panel (the Panel) are based on the results of these studies.

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The COVID-19 Treatment Guidelines Panel’s Statement on the

(2 days ago) Health care providers are encouraged to discuss participation in bamlanivimab clinical trials with their patients. • Given the possibility of a limited supply of bamlanivimab, as well as challenges distributing and administering the drug, patients at highest risk for COVID-19 progression should be prioritized for

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Lopinavir/Ritonavir and Other HIV Protease Inhibitors

(9 days ago) Lopinavir/Ritonavir and Other HIV Protease Inhibitors. Last Updated: February 11, 2021. The replication of SARS-CoV-2 depends on the cleavage of polyproteins into an RNA-dependent RNA polymerase and a helicase. 1 Two proteases are responsible for this cleavage: 3-chymotrypsin-like protease (3CLpro) and papain-like protease (PLpro). Lopinavir/ritonavir and darunavir/cobicistat have …

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Epidemiology

(1 days ago) the presence of chronic medical conditions. Among those with available data on health conditions, 32% had cardiovascular disease, 30% had diabetes, and 18% had chronic lung disease. Other conditions that may lead to a high risk for severe COVID-19 include cancer, kidney disease, obesity, sickle cell disease, and other immunocompromising conditions.

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Table: Characteristics of Anti-SARS-CoV-2 Antibody

(3 days ago) Only for administration in health care settings by qualified health care providers who have immediate access to medications to treat a severe infusion reaction and emergency medical services. Monitor patient during the infusion and for ≥1 hour after the infusion is completed.

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Table: Corticosteroids Clinical Data COVID-19 Treatment

(7 days ago) Review clinical data on the use of corticosteroids for the treatment of COVID-19.

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Coronavirus Disease 2019 (COVID-19) Treatment Guidelines

(9 days ago) Health. Available at https://www.covid19treatmentguidelines.nih.gov/. Accessed [insert date]. The COVID-19 Treatment Guidelines Panel regularly updates the recommendations in these guidelines as new information on the management of COVID-19 becomes available. The most recent version of the guidelines can be found on the

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Extracorporeal Membrane Oxygenation COVID-19 Treatment

(7 days ago) Extracorporeal Membrane Oxygenation. Last Updated: December 17, 2020. Recommendation. There are insufficient data to recommend either for or against the use of extracorporeal membrane oxygenation (ECMO) in adults with COVID-19 and refractory hypoxemia.

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Coronavirus Disease 2019 (COVID-19) Treatment Guidelines

(9 days ago) ensure that health care providers, patients, and policy experts have the most recent information regarding the optimal management of COVID-19 (see the Panel Roster for a list of Panel members). New Guidelines sections and recommendations and updates to existing Guidelines sections are developed by working groups of Panel members.

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Chloroquine or Hydroxychloroquine COVID-19 Treatment

(8 days ago) Nguyen LS, Dolladille C, Drici MD, et al. Cardiovascular toxicities associated with hydroxychloroquine and azithromycin: an analysis of the World Health Organization pharmacovigilance database. Circulation . 2020;142(3):303-305.

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Pregnancy COVID-19 Treatment Guidelines

(7 days ago) Epidemiology of COVID-19 in Pregnancy. Initial reports of COVID-19 disease acquired in the third trimester were reassuring, although most early data were limited to case reports and case series. 5-7 Since that time, a large population-based cohort study in the United Kingdom evaluated outcomes in pregnant women hospitalized with confirmed severe acute respiratory syndrome coronavirus type 2

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Immunomodulators COVID-19 Treatment Guidelines

(6 days ago) Summary Recommendations; Summary Recommendations See Therapeutic Management of Patients with COVID-19 for the COVID-19 Treatment Guidelines Panel’s (the Panel’s) recommendations on the use of the following:. Baricitinib in combination with remdesivir when corticosteroids cannot be used,

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Table: Chloroquine or Hydroxychloroquine Clinical Data

(3 days ago) This study evaluated 1 health care system with an institutional protocol for HCQ and AZM use. Because the study was not randomized and not blinded, there is a possibility of residual confounding. There was a lower rate of ICU admission among patients who did not receive HCQ, which suggests that this group may have received less aggressive care.

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